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Introduction

Joints: From prevention to regeneration

About Us

Palatinose™: Sustained Energy Supply

The Science behind Superfoods

Our Caravan of Dreams

Exercise is Medicine

Artificial and Natural Sweeteners: Research clarifies effects

Activate your Brain

Whey Protein: Beyond Sport

References

WHEY PROTEIN. BEYOND SPORT
A world of possibilities
  1. 1. Steinitz, Leslie. “Making Muscular Machines with Nitrogenous Nutrition”. In: Food and Material Culture: Proceedings of the Oxford Symposium on Food and Cookery. Prospect Books; 2014
  2. 2. Solak BB; Akin N. Health Benefits of Whey Protein: A Review. Journal of Food Science and Engineering. 2012
  3. 3. Rogero M, Tirapegui J. Aspectos atuais sobre aminoácidos de cadeia ramificada e exercício físico Marcelo. RBCF. 2008
  4. 4. Haraguchi FK, et al. Proteínas do soro do leite: composição, propriedades nutricionais, aplicações no esporte e benefícios para a saúde humana. Revista de Nutrição.2006
  5. 5. Krissansen GW. Emerging health properties of whey proteins and their clinical implications. The Journal of the American College of Nutrition. 2007
  6. 6. Tai CS, et al. β-Lactoglobulin Influences Human Immunity and Promotes Cell Proliferation. BioMed Research International. 2016. Doi:10.1155/2016/7123587
  7. 7. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised controlled trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  8. 8. Mulder AM, et al. Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males. Nutrition Research. 2008
  9. 9. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  10. 10. Siqueiros-Cendón T, et al. Immunomodulatory effects of lactoferrin. Acta Pharmacologica Sinica. 2014. Doi:10.1038/ aps.2013.200
  11. 11. Satué-Gracia MT, et al. Lactoferrin in Infant Formulas: Effect on Oxidation. Journal of Agricultural and Food Chemistry. 2000
  12. 12. Rezk M, et al. Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial Journal of Maternal-Fetal & Neonatal Medicine. 2015. Doi:10.3109/14767058.20 15.1049149.
  13. 13. “Whey Protein Institute” Available in: http://wheyproteininstitute. org Accessed May 2018
  14. 14. Zapata RC, et al. Whey Protein Components - Lactalbumin and Lactoferrin - Improve Energy Balance and Metabolism. Scientific Reports. 2017.
  15. Doi:10.1038/s41598-017-09781-2
  16. 15. Chaudière J; Ferrari-Iliou R. Intracellular antioxidants: from chemical to biochemical mechanisms. Food and Chemical Toxicology. 1999
  17. 16. Kent KD, et al. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicology In Vitro. 2003
  18. 17. Fraternale A, et al. Glutathione and glutathione derivatives in immunotherapy. The Journal of Biological Chemistry. 2016. Doi:10.1515/hsz-2016-0202
  19. 18. Dröge W; Holm E. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEB Journal; 1997. Doi:10.1096/ fasebj.11.13.9367343
  20. 19. Fraternale A, et al. Antiviral and Immunomodulatory Properties of New Pro-Glutathione (GSH) Molecules. Current Medicinal Chemistry. 2006
  21. 20. Sekhar RV, et al. Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine. Diabetes Care. 2011
  22. 21. Sekhar RV, et al. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. The American Journal of Clinical Nutrition. 2017
  23. 22. Micke P, et al. Efeitos da suplementação a longo prazo com proteínas do soro sobre os níveis plasmáticos de glutationa em pacientes infectados pelo HIV. European Journal of Nutrition. 2012
  24. 23. Fraternale A, et al. Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral Research. 2008. Doi:10.1016/j. antiviral.2007.11.004
  25. 24. Rusu D, et al. A bovine whey protein extract can enhance innate immunity by priming normal human blood neutrophils. The Journal of Nutrition. 2009
  26. 25. Migliore-Samour D, et al. Effects of tripeptides derived from milk proteins on polymorphonuclear oxidative and phosphoinositide metabolisms. Biochemical Pharmacology. 1992
  27. 26. Yang Y, et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. British Journal of Nutrition. 2012
  28. 27. Konopka AR; Harber MP. Skeletal muscle hypertrophy after aerobic exercise training. Exercise Sport Sciences Reviews. 2014. Doi:10.1249/ JES.0000000000000007
  29. 28. Morton RW, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. British Journal of Sports Medicine. 2017. Doi:10.1136/bjsports-2017-097608
  30. 29. Denison HJ, et al. Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clinical Interventions in Aging. 2015. Doi:10.2147/CIA.S55842
  31. 30. Tieland M, et al. Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement. European Journal of Nutrition. 2012. Doi:10.1007/s00394-011-0203-6
  32. 31. Karelis A, et al. Effect of cysteine-rich whey protein (Immunocal®) supplementation in combination with resistance training on muscle strength and lean body mass in non-frail elderly subjects: A randomized, double-blind controlled study. The Journal of Nutrition, Health & Aging. 2015
  33. 32. Zwirzitz A, et al. Lactoferrin is a natural inhibitor of plasminogen activation. Journal of Biological Chemistry. 2018. Doi:10.1074/jbc.RA118.003145
  34. 33. Wasilewska J, et al. The exogenous opioid peptides and DPPIV serum activity in infants with apnoea expressed as apparent life threatening events (ALTE). Neuropeptides. 2011. Doi:10.1016/j. npep.2011.01.005
  35. 34. Kurek M, et al. “A naturally occurring opioid peptide from cow’s milk, beta-casomorphine-7, is a direct histamine releaser in man”. International Archives Allergy and Immunology. 1992. Doi:10.1159/000236106
  36. 35. Clemens RA, et al. Milk and Milk Products in Human Nutrition. Nestlé Nutrition Institute Workshop, Pediatric Program. 2011. Doi:10.1159/000325584
  37. 36. Kayser H; Meisel H. Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins. FEBS Letters. 1996. Doi:10.1016/0014-5793(96)00207-4
  38. 37. Oben J; Anderson ML. An open label study to determine the effects of an oral proteolytic enzyme system on whey protein concentrate metabolism in healthy males. Journal of the International Society of Sports Nutrition. 2008. Doi:10.1186/1550-2783-5-10
  39. 38. Rocha GF, et al. Potential antioxidant peptides produced from whey hydrolysis with an immobilized aspartic protease from Salpichroa origanifolia fruits. Food Chemistry. 2017. Doi:10.1016/j. foodchem.2017.05.112
  40. 39. Cook RC; Blinman TA. Nutritional support of the pediatric trauma patient. Seminar Pediatric Surgery. 2010. Doi:10.1053/j. sempedsurg.2010.06.001
  41. 40. Martin V, et al. Whey Proteins Are More Efficient than Casein in the Recovery of Muscle Functional Properties following a Casting Induced Muscle Atrophy. PLoS One. 2013
  42. 41. Campbell BI, et al. Effects of High vs. Low Protein Intake on Body Composition and Maximal Strength in Aspiring Female Physique Athletes Engaging in an 8-Week Resistance Training Program. International Journal of Sport Nutrition Exercise Metabolism. 2018. Doi:10.1123/ijsnem.2017-0389
  43. 42. Alexander DD. Partially hydrolyzed 100% whey protein infant formula and atopic dermatitis risk reduction: a systematic review of the literature. Nutrition Reviews. 2010. Doi:10.1111/j.1753-4887.2010.00281.x
  44. 43. Savino F, et al. Reduction of crying episodes owing to infantile colic: A randomized controlled study on the efficacy of a new infant formula. European Journal of Clinical Nutrition. 2006
  45. 44. Sheikholeslami VD; Ahmadi KGF. Changes in antioxidant status and cardiovascular risk factors of overweight young men after six weeks supplementation of whey protein isolate and resistance training. Appetite. 2012. Doi:10.1016/j.appet.2012.08.005
  46. 45. Bortolotti M, et al. Effects of a whey protein supplementation on intrahepatocellular lipids in obese female patients. Clinical Nutrition. 2011. Doi:10.1016/j.clnu.2011.01.006
  47. 46. Chitapanarux T, et al. Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. Journal of Gastroenterology and Hepatology. 2009. Doi:10.1111/j.1440- 1746.2009.05865.x
  48. 47. Pal S, et al. Acute effects of whey protein isolate on cardiovascular risk factors in overweight, post-menopausal women. Atherosclerosis. 2010. Doi:10.1016/j.atherosclerosis.2010.05.032
  49. 48. Paterson MA, et al. Increasing the protein quantity in a meal results in dose-dependent effects on postprandial glucose levels in individuals with Type 1 diabetes mellitus. Diabetic Medicine. 2017. Doi:10.1111/dme.13347
  50. 49. Jakubowicz D, et al. OR12-3: Whey protein induces greater reduction of postprandial glycemia and HbA1c, weight loss and satiety compared to other protein sources in type 2 diabetes. Endocrine Reviews. 2016
  51. 50. Mignone LE, et al. Whey protein: The “whey” forward for treatment of type 2 diabetes? World Journal of Diabetes, 2015. Doi:104239/wjd. v6.i14.1274
  52. 51. “Two small studies indicate benefits of whey protein for type 2 diabetes control.” Available in: diabetes.co.uk/news/2017/mar/ two-small-studies-indicate-benefits-of-whey-protein-for-type-2- diabetes-control-94525480.html Accessed 05/2018
  53. 52. Wong CW; Watson DL. Immunodulatory effects of dietary whey proteins in mice. Journal of Dairy Research. 1995
  54. 53. Parker NT; Goodrum KJ. A comparison of casein, lactalbumin, and soy protein effect on the immune response to a T- dependent antigen. Source: National Agricultural Library. 1990
  55. 54. Burd NA, et al. Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. British Journal of Nutrition. 2012
  56. 55. Rosaneli CF, et al. Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion. Journal of Medical Food. 2002
  57. 56. Marshall K. Therapeutic applications of whey protein. Alternative Medicine Review. 2004
  58. 57. Parodi PW. A role for milk proteins and their peptides in cancer prevention. Current Pharmaceutical Design. 2007
  59. 58. Dillon EL, et al. Cancer cachexia and anabolic interventions: a case report. Journal of Cachexia, Sarcopenia and Muscle. 2012. Doi:10.1007/s13539- 012-0066-6
  60. 59. King DG, et al. A small dose of whey protein co-ingested with mixed-macronutrient breakfast and lunch meals improves postprandial glycemia and suppresses appetite in men with type 2 diabetes: a randomized controlled trial. The American Journal of Clinical Nutrition. 2018
 

Download contents

Introduction

Joints: From prevention to regeneration

About Us

Palatinose™: Sustained Energy Supply

The Science behind Superfoods

Our Caravan of Dreams

Exercise is Medicine

Artificial and Natural Sweeteners: Research clarifies effects

Activate your Brain

Whey Protein: Beyond Sport

References

WHEY PROTEIN. BEYOND SPORT
A world of possibilities
  1. 1. Steinitz, Leslie. “Making Muscular Machines with Nitrogenous Nutrition”. In: Food and Material Culture: Proceedings of the Oxford Symposium on Food and Cookery. Prospect Books; 2014
  2. 2. Solak BB; Akin N. Health Benefits of Whey Protein: A Review. Journal of Food Science and Engineering. 2012
  3. 3. Rogero M, Tirapegui J. Aspectos atuais sobre aminoácidos de cadeia ramificada e exercício físico Marcelo. RBCF. 2008
  4. 4. Haraguchi FK, et al. Proteínas do soro do leite: composição, propriedades nutricionais, aplicações no esporte e benefícios para a saúde humana. Revista de Nutrição.2006
  5. 5. Krissansen GW. Emerging health properties of whey proteins and their clinical implications. The Journal of the American College of Nutrition. 2007
  6. 6. Tai CS, et al. β-Lactoglobulin Influences Human Immunity and Promotes Cell Proliferation. BioMed Research International. 2016. Doi:10.1155/2016/7123587
  7. 7. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised controlled trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  8. 8. Mulder AM, et al. Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males. Nutrition Research. 2008
  9. 9. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  10. 10. Siqueiros-Cendón T, et al. Immunomodulatory effects of lactoferrin. Acta Pharmacologica Sinica. 2014. Doi:10.1038/ aps.2013.200
  11. 11. Satué-Gracia MT, et al. Lactoferrin in Infant Formulas: Effect on Oxidation. Journal of Agricultural and Food Chemistry. 2000
  12. 12. Rezk M, et al. Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial Journal of Maternal-Fetal & Neonatal Medicine. 2015. Doi:10.3109/14767058.20 15.1049149.
  13. 13. “Whey Protein Institute” Available in: http://wheyproteininstitute. org Accessed May 2018
  14. 14. Zapata RC, et al. Whey Protein Components - Lactalbumin and Lactoferrin - Improve Energy Balance and Metabolism. Scientific Reports. 2017.
  15. Doi:10.1038/s41598-017-09781-2
  16. 15. Chaudière J; Ferrari-Iliou R. Intracellular antioxidants: from chemical to biochemical mechanisms. Food and Chemical Toxicology. 1999
  17. 16. Kent KD, et al. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicology In Vitro. 2003
  18. 17. Fraternale A, et al. Glutathione and glutathione derivatives in immunotherapy. The Journal of Biological Chemistry. 2016. Doi:10.1515/hsz-2016-0202
  19. 18. Dröge W; Holm E. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEB Journal; 1997. Doi:10.1096/ fasebj.11.13.9367343
  20. 19. Fraternale A, et al. Antiviral and Immunomodulatory Properties of New Pro-Glutathione (GSH) Molecules. Current Medicinal Chemistry. 2006
  21. 20. Sekhar RV, et al. Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine. Diabetes Care. 2011
  22. 21. Sekhar RV, et al. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. The American Journal of Clinical Nutrition. 2017
  23. 22. Micke P, et al. Efeitos da suplementação a longo prazo com proteínas do soro sobre os níveis plasmáticos de glutationa em pacientes infectados pelo HIV. European Journal of Nutrition. 2012
  24. 23. Fraternale A, et al. Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral Research. 2008. Doi:10.1016/j. antiviral.2007.11.004
  25. 24. Rusu D, et al. A bovine whey protein extract can enhance innate immunity by priming normal human blood neutrophils. The Journal of Nutrition. 2009
  26. 25. Migliore-Samour D, et al. Effects of tripeptides derived from milk proteins on polymorphonuclear oxidative and phosphoinositide metabolisms. Biochemical Pharmacology. 1992
  27. 26. Yang Y, et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. British Journal of Nutrition. 2012
  28. 27. Konopka AR; Harber MP. Skeletal muscle hypertrophy after aerobic exercise training. Exercise Sport Sciences Reviews. 2014. Doi:10.1249/ JES.0000000000000007
  29. 28. Morton RW, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. British Journal of Sports Medicine. 2017. Doi:10.1136/bjsports-2017-097608
  30. 29. Denison HJ, et al. Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clinical Interventions in Aging. 2015. Doi:10.2147/CIA.S55842
  31. 30. Tieland M, et al. Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement. European Journal of Nutrition. 2012. Doi:10.1007/s00394-011-0203-6
  32. 31. Karelis A, et al. Effect of cysteine-rich whey protein (Immunocal®) supplementation in combination with resistance training on muscle strength and lean body mass in non-frail elderly subjects: A randomized, double-blind controlled study. The Journal of Nutrition, Health & Aging. 2015
  33. 32. Zwirzitz A, et al. Lactoferrin is a natural inhibitor of plasminogen activation. Journal of Biological Chemistry. 2018. Doi:10.1074/jbc.RA118.003145
  34. 33. Wasilewska J, et al. The exogenous opioid peptides and DPPIV serum activity in infants with apnoea expressed as apparent life threatening events (ALTE). Neuropeptides. 2011. Doi:10.1016/j. npep.2011.01.005
  35. 34. Kurek M, et al. “A naturally occurring opioid peptide from cow’s milk, beta-casomorphine-7, is a direct histamine releaser in man”. International Archives Allergy and Immunology. 1992. Doi:10.1159/000236106
  36. 35. Clemens RA, et al. Milk and Milk Products in Human Nutrition. Nestlé Nutrition Institute Workshop, Pediatric Program. 2011. Doi:10.1159/000325584
  37. 36. Kayser H; Meisel H. Stimulation of human peripheral blood lymphocytes by bioactive peptides derived from bovine milk proteins. FEBS Letters. 1996. Doi:10.1016/0014-5793(96)00207-4
  38. 37. Oben J; Anderson ML. An open label study to determine the effects of an oral proteolytic enzyme system on whey protein concentrate metabolism in healthy males. Journal of the International Society of Sports Nutrition. 2008. Doi:10.1186/1550-2783-5-10
  39. 38. Rocha GF, et al. Potential antioxidant peptides produced from whey hydrolysis with an immobilized aspartic protease from Salpichroa origanifolia fruits. Food Chemistry. 2017. Doi:10.1016/j. foodchem.2017.05.112
  40. 39. Cook RC; Blinman TA. Nutritional support of the pediatric trauma patient. Seminar Pediatric Surgery. 2010. Doi:10.1053/j. sempedsurg.2010.06.001
  41. 40. Martin V, et al. Whey Proteins Are More Efficient than Casein in the Recovery of Muscle Functional Properties following a Casting Induced Muscle Atrophy. PLoS One. 2013
  42. 41. Campbell BI, et al. Effects of High vs. Low Protein Intake on Body Composition and Maximal Strength in Aspiring Female Physique Athletes Engaging in an 8-Week Resistance Training Program. International Journal of Sport Nutrition Exercise Metabolism. 2018. Doi:10.1123/ijsnem.2017-0389
  43. 42. Alexander DD. Partially hydrolyzed 100% whey protein infant formula and atopic dermatitis risk reduction: a systematic review of the literature. Nutrition Reviews. 2010. Doi:10.1111/j.1753-4887.2010.00281.x
  44. 43. Savino F, et al. Reduction of crying episodes owing to infantile colic: A randomized controlled study on the efficacy of a new infant formula. European Journal of Clinical Nutrition. 2006
  45. 44. Sheikholeslami VD; Ahmadi KGF. Changes in antioxidant status and cardiovascular risk factors of overweight young men after six weeks supplementation of whey protein isolate and resistance training. Appetite. 2012. Doi:10.1016/j.appet.2012.08.005
  46. 45. Bortolotti M, et al. Effects of a whey protein supplementation on intrahepatocellular lipids in obese female patients. Clinical Nutrition. 2011. Doi:10.1016/j.clnu.2011.01.006
  47. 46. Chitapanarux T, et al. Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. Journal of Gastroenterology and Hepatology. 2009. Doi:10.1111/j.1440- 1746.2009.05865.x
  48. 47. Pal S, et al. Acute effects of whey protein isolate on cardiovascular risk factors in overweight, post-menopausal women. Atherosclerosis. 2010. Doi:10.1016/j.atherosclerosis.2010.05.032
  49. 48. Paterson MA, et al. Increasing the protein quantity in a meal results in dose-dependent effects on postprandial glucose levels in individuals with Type 1 diabetes mellitus. Diabetic Medicine. 2017. Doi:10.1111/dme.13347
  50. 49. Jakubowicz D, et al. OR12-3: Whey protein induces greater reduction of postprandial glycemia and HbA1c, weight loss and satiety compared to other protein sources in type 2 diabetes. Endocrine Reviews. 2016
  51. 50. Mignone LE, et al. Whey protein: The “whey” forward for treatment of type 2 diabetes? World Journal of Diabetes, 2015. Doi:104239/wjd. v6.i14.1274
  52. 51. “Two small studies indicate benefits of whey protein for type 2 diabetes control.” Available in: diabetes.co.uk/news/2017/mar/ two-small-studies-indicate-benefits-of-whey-protein-for-type-2- diabetes-control-94525480.html Accessed 05/2018
  53. 52. Wong CW; Watson DL. Immunodulatory effects of dietary whey proteins in mice. Journal of Dairy Research. 1995
  54. 53. Parker NT; Goodrum KJ. A comparison of casein, lactalbumin, and soy protein effect on the immune response to a T- dependent antigen. Source: National Agricultural Library. 1990
  55. 54. Burd NA, et al. Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. British Journal of Nutrition. 2012
  56. 55. Rosaneli CF, et al. Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion. Journal of Medical Food. 2002
  57. 56. Marshall K. Therapeutic applications of whey protein. Alternative Medicine Review. 2004
  58. 57. Parodi PW. A role for milk proteins and their peptides in cancer prevention. Current Pharmaceutical Design. 2007
  59. 58. Dillon EL, et al. Cancer cachexia and anabolic interventions: a case report. Journal of Cachexia, Sarcopenia and Muscle. 2012. Doi:10.1007/s13539- 012-0066-6
  60. 59. King DG, et al. A small dose of whey protein co-ingested with mixed-macronutrient breakfast and lunch meals improves postprandial glycemia and suppresses appetite in men with type 2 diabetes: a randomized controlled trial. The American Journal of Clinical Nutrition. 2018
 

Download contents

Introduction

Joints: From prevention to regeneration

About Us

Palatinose™: Sustained Energy Supply

The Science behind Superfoods

Our Caravan of Dreams

Exercise is Medicine

Artificial and Natural Sweeteners: Research clarifies effects

Activate your Brain

Whey Protein: Beyond Sport

References

WHEY PROTEIN. BEYOND SPORT
A world of possibilities
  1. 1. Steinitz, Leslie. “Making Muscular Machines with Nitrogenous Nutrition”. In: Food and Material Culture: Proceedings of the Oxford Symposium on Food and Cookery. Prospect Books; 2014
  2. 2. Solak BB; Akin N. Health Benefits of Whey Protein: A Review. Journal of Food Science and Engineering. 2012
  3. 3. Rogero M, Tirapegui J. Aspectos atuais sobre aminoácidos de cadeia ramificada e exercício físico Marcelo. RBCF. 2008
  4. 4. Haraguchi FK, et al. Proteínas do soro do leite: composição, propriedades nutricionais, aplicações no esporte e benefícios para a saúde humana. Revista de Nutrição.2006
  5. 5. Krissansen GW. Emerging health properties of whey proteins and their clinical implications. The Journal of the American College of Nutrition. 2007
  6. 6. Tai CS, et al. β-Lactoglobulin Influences Human Immunity and Promotes Cell Proliferation. BioMed Research International. 2016. Doi:10.1155/2016/7123587
  7. 7. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised controlled trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  8. 8. Mulder AM, et al. Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males. Nutrition Research. 2008
  9. 9. Cox AJ, et al. Effects of short-term supplementation with bovine lactoferrin and/or immunoglobulins on body mass and metabolic measures: a randomised trial. International Journal of Food Sciences and Nutrition. 2016. Doi:10.1080/09637486.2016.1224230
  10. 10. Siqueiros-Cendón T, et al. Immunomodulatory effects of lactoferrin. Acta Pharmacologica Sinica. 2014. Doi:10.1038/ aps.2013.200
  11. 11. Satué-Gracia MT, et al. Lactoferrin in Infant Formulas: Effect on Oxidation. Journal of Agricultural and Food Chemistry. 2000
  12. 12. Rezk M, et al. Lactoferrin versus ferrous sulphate for the treatment of iron deficiency anemia during pregnancy: a randomized clinical trial Journal of Maternal-Fetal & Neonatal Medicine. 2015. Doi:10.3109/14767058.20 15.1049149.
  13. 13. “Whey Protein Institute” Available in: http://wheyproteininstitute. org Accessed May 2018
  14. 14. Zapata RC, et al. Whey Protein Components - Lactalbumin and Lactoferrin - Improve Energy Balance and Metabolism. Scientific Reports. 2017.
  15. Doi:10.1038/s41598-017-09781-2
  16. 15. Chaudière J; Ferrari-Iliou R. Intracellular antioxidants: from chemical to biochemical mechanisms. Food and Chemical Toxicology. 1999
  17. 16. Kent KD, et al. Effect of whey protein isolate on intracellular glutathione and oxidant-induced cell death in human prostate epithelial cells. Toxicology In Vitro. 2003
  18. 17. Fraternale A, et al. Glutathione and glutathione derivatives in immunotherapy. The Journal of Biological Chemistry. 2016. Doi:10.1515/hsz-2016-0202
  19. 18. Dröge W; Holm E. Role of cysteine and glutathione in HIV infection and other diseases associated with muscle wasting and immunological dysfunction. FASEB Journal; 1997. Doi:10.1096/ fasebj.11.13.9367343
  20. 19. Fraternale A, et al. Antiviral and Immunomodulatory Properties of New Pro-Glutathione (GSH) Molecules. Current Medicinal Chemistry. 2006
  21. 20. Sekhar RV, et al. Glutathione Synthesis Is Diminished in Patients With Uncontrolled Diabetes and Restored by Dietary Supplementation With Cysteine and Glycine. Diabetes Care. 2011
  22. 21. Sekhar RV, et al. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. The American Journal of Clinical Nutrition. 2017
  23. 22. Micke P, et al. Efeitos da suplementação a longo prazo com proteínas do soro sobre os níveis plasmáticos de glutationa em pacientes infectados pelo HIV. European Journal of Nutrition. 2012
  24. 23. Fraternale A, et al. Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral Research. 2008. Doi:10.1016/j. antiviral.2007.11.004
  25. 24. Rusu D, et al. A bovine whey protein extract can enhance innate immunity by priming normal human blood neutrophils. The Journal of Nutrition. 2009
  26. 25. Migliore-Samour D, et al. Effects of tripeptides derived from milk proteins on polymorphonuclear oxidative and phosphoinositide metabolisms. Biochemical Pharmacology. 1992
  27. 26. Yang Y, et al. Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. British Journal of Nutrition. 2012
  28. 27. Konopka AR; Harber MP. Skeletal muscle hypertrophy after aerobic exercise training. Exercise Sport Sciences Reviews. 2014. Doi:10.1249/ JES.0000000000000007
  29. 28. Morton RW, et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. British Journal of Sports Medicine. 2017. Doi:10.1136/bjsports-2017-097608
  30. 29. Denison HJ, et al. Prevention and optimal management of sarcopenia: a review of combined exercise and nutrition interventions to improve muscle outcomes in older people. Clinical Interventions in Aging. 2015. Doi:10.2147/CIA.S55842
  31. 30. Tieland M, et al. Dietary protein intake in community-dwelling, frail, and institutionalized elderly people: scope for improvement. European Journal of Nutrition. 2012. Doi:10.1007/s00394-011-0203-6
  32. 31. Karelis A, et al. Effect of cysteine-rich whey protein (Immunocal®) supplementation in combination with resistance training on muscle strength and lean body mass in non-frail elderly subjects: A randomized, double-blind controlled study. The Journal of Nutrition, Health & Aging. 2015
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